Ideally, the targeted receptor- or carrier-mediated transport processes for brain targeting should occur exclusively at the BBB to avoid off-target delivery
10.18053/jctres.03.2017S1.002 J
This review evaluates the therapeutic potential of GM-targeted interventions, including probiotics, prebiotics, and fecal microbiota transplantation, and underscores the GM as a pivotal therapeutic target, emphasizing that future therapeutic strategies for OP must incorporate the interconnected GM-bone axis for efficacious prevention and treatment
The authors discovered the ASHMI, like MSSM-002, has broad spectrum therapeutic effects on major mechanisms involved in allergic asthma, including airway hyperreactivity, pulmonary inflammation, and airway remodeling, and the downregulation of Th2 responses [96]